Is spray volume important to your patients?
Clinical benefit has not been demonstrated regarding spray volume.
Recommended Dymista dosing for children and adults is 1 spray (0.137 mL which contains 137 mcg of azelastine hydrochloride and 50 mcg of fluticasone propionate) per nostril, twice daily.1
Spray volumes at the maximum recommended adult dose1-3
- Astelin® (azelastine HCI) = 0.548 mL
- Flonase® = 0.400 mL
- Astelin® + Flonase® = 0.948 mL
- Dymista = 0.274 mL
- Dymista volume is less than 1/3 that of Astelin® and Flonase® taken sequentially✶
At the maximum recommended adult dose of 2 sprays per nostril.
References: 1. Dymista [package insert]. Somerset, NJ: Meda Pharmaceuticals Inc., a Viatris Company; 2021. 2. Flonase [package insert]. Research Triangle Park, NC: GlaxoSmithKline; 2020. 3. Astelin [package insert]. Somerset, NJ: Meda Pharmaceuticals Inc., a Viatris Company; 2019.